CovidV2, Main, Exploration, bibRecord, 001F62

Australian Antigen and Autoantibodies in Chronic Hepatitis

Identifieur interne : 001F62 ( Main/Exploration ); précédent : 001F61; suivant : 001F63

Australian Antigen and Autoantibodies in Chronic Hepatitis

Auteurs : T. L. Vischer

Source :

British Medical Journal [ 0007-1447 ] ; 1970-06-20.

RBID : ISTEX:176D3080730CA3B8767509368EA0CE8A1CEECD73

English descriptors

Teeft :
- Acute hepatitis, Antibody, Antigen, Antihuman immunoglobulin serum, Antinuclear, Antinuclear factor, Antinuclear factors, Assay conditions, Australia antigen, Autoimmune processes, Biliary, Biliary cirrhosis, Biopsy, Blood donors, Chronic, Chronic hepatitis, Chronic inflammation, Cirrhosis, Dehydrogenase, Doniach, Experimental immunology, Growth rate, Hepatitis, Hepatitis virus, Histological examination, Hormone responsiveness, Lactate dehydrogenase, Lancet, Liver diseases, Mutual exclusion, Phosphohexose isomerase, Primary biliary cirrhosis, Professor soulier, Reconvalescence period, Reference antisera, References blumberg, Room temperature, Study group, Such antibodies, Swiss society, Systemic lupus erythematosus, Total protein, Tumour, Various autoantibodies, Various hospital patients, Yournal.

Abstract

The sera of 110 patients with chronic hepatitis and adequate controls were examined for antibodies to smooth muscle (S.M.), mitochondria (M.), and for antinuclear factors by the immunofluorescence method, and for Australia (Au(1)) antigen by a modified micro-Ouchterlony immunodiffusion technique. Twelve out of 13 patients with primary biliary cirrhosis had M. antibodies, two had antinuclear factor, and none had Au(1) in their sera. In chronic aggressive hepatitis 23·5% of the sera contained antinuclear factor, 13% S.M. antibodies, 10·5% M. antibodies, and 22% Au(1) antigen. Of the 12 patients with chronic persistent hepatitis, one had antinuclear factor, one S.M. antibodies, and three Au(1) antigen. The most striking finding was a mutual exclusion between Au(1) antigen and M. and S.M. antibodies. None of the 33 patients with one or the other form of chronic hepatitis and M. or S.M. antibodies had Au(1) antigen; 22 out of 77 (28%) patients without such antibodies were positive.

Url:

DOI: 10.1136/bmj.2.5711.695

Affiliations:

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<term>Antinuclear factor</term>
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<term>Chronic</term>
<term>Chronic hepatitis</term>
<term>Chronic inflammation</term>
<term>Cirrhosis</term>
<term>Dehydrogenase</term>
<term>Doniach</term>
<term>Experimental immunology</term>
<term>Growth rate</term>
<term>Hepatitis</term>
<term>Hepatitis virus</term>
<term>Histological examination</term>
<term>Hormone responsiveness</term>
<term>Lactate dehydrogenase</term>
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<term>Liver diseases</term>
<term>Mutual exclusion</term>
<term>Phosphohexose isomerase</term>
<term>Primary biliary cirrhosis</term>
<term>Professor soulier</term>
<term>Reconvalescence period</term>
<term>Reference antisera</term>
<term>References blumberg</term>
<term>Room temperature</term>
<term>Study group</term>
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<front><div type="abstract" xml:lang="en">The sera of 110 patients with chronic hepatitis and adequate controls were examined for antibodies to smooth muscle (S.M.), mitochondria (M.), and for antinuclear factors by the immunofluorescence method, and for Australia (Au(1)) antigen by a modified micro-Ouchterlony immunodiffusion technique. Twelve out of 13 patients with primary biliary cirrhosis had M. antibodies, two had antinuclear factor, and none had Au(1) in their sera. In chronic aggressive hepatitis 23·5% of the sera contained antinuclear factor, 13% S.M. antibodies, 10·5% M. antibodies, and 22% Au(1) antigen. Of the 12 patients with chronic persistent hepatitis, one had antinuclear factor, one S.M. antibodies, and three Au(1) antigen. The most striking finding was a mutual exclusion between Au(1) antigen and M. and S.M. antibodies. None of the 33 patients with one or the other form of chronic hepatitis and M. or S.M. antibodies had Au(1) antigen; 22 out of 77 (28%) patients without such antibodies were positive.</div>
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Australian Antigen and Autoantibodies in Chronic Hepatitis

Australian Antigen and Autoantibodies in Chronic Hepatitis

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration Covid (26 mars)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.